SAP155-Mediated Splicing of FUSE-Binding Protein-Interacting Repressor Serves as a Molecular Switch for c-myc Gene Expression

The Far UpStream Element (FUSE)-binding protein-interacting repressor (FIR), a c-myc transcriptional suppressor, is alternatively spliced removing the transcriptional repression domain within exon 2 (FIRΔexon2) in colorectal cancers. SAP155 is a subunit of the essential splicing factor 3b (SF3b) sub...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Matsushita, Kazuyuki, Kajiwara, Toshiko, Tamura, Mai, Satoh, Mamoru, Tanaka, Nobuko, Tomonaga, Takeshi, Matsubara, Hisahiro, Shimada, Hideaki, Yoshimoto, Rei, Ito, Akihiro, Kubo, Shuji, Natsume, Tohru, Levens, David, Yoshida, Minoru, Nomura, Fumio
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469880/
https://ncbi.nlm.nih.gov/pubmed/22496461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0462
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