Non-transmissible Sendai virus vector encoding c-myc suppressor FBP-interacting repressor for cancer therapy

AIM: To investigate a novel therapeutic strategy to target and suppress c-myc in human cancers using far up stream element (FUSE)-binding protein-interacting repressor (FIR). METHODS: Endogenous c-Myc suppression and apoptosis induction by a transient FIR-expressing vector was examined in vivo via a...

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Main Authors: Matsushita, Kazuyuki, Shimada, Hideaki, Ueda, Yasuji, Inoue, Makoto, Hasegawa, Mamoru, Tomonaga, Takeshi, Matsubara, Hisahiro, Nomura, Fumio
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989966/
https://ncbi.nlm.nih.gov/pubmed/24764668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i15.4316
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