TRAP1 Regulates Wnt/β-Catenin Pathway through LRP5/6 Receptors Expression Modulation

Wnt/β-Catenin signaling is involved in embryonic development, regeneration, and cellular differentiation and is responsible for cancer stemness maintenance. The HSP90 molecular chaperone TRAP1 is upregulated in 60–70% of human colorectal carcinomas (CRCs) and favors stem cells maintenance, modulatin...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Lettini, Giacomo, Condelli, Valentina, Pietrafesa, Michele, Crispo, Fabiana, Zoppoli, Pietro, Maddalena, Francesca, Laurenzana, Ilaria, Sgambato, Alessandro, Esposito, Franca, Landriscina, Matteo
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589514/
https://ncbi.nlm.nih.gov/pubmed/33065966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207526
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