Increased intestinal permeability and gut dysbiosis in the R6/2 mouse model of Huntington’s disease

Huntington’s disease (HD) is a progressive, multifaceted neurodegenerative disease associated with weight loss and gut problems. Under healthy conditions, tight junction (TJ) proteins maintain the intestinal barrier integrity preventing bacterial translocation from the intestinal lumen to the system...

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Vydáno v:Sci Rep
Hlavní autoři: Stan, Tiberiu Loredan, Soylu-Kucharz, Rana, Burleigh, Stephen, Prykhodko, Olena, Cao, Ling, Franke, Naomi, Sjögren, Marie, Haikal, Caroline, Hållenius, Frida, Björkqvist, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589489/
https://ncbi.nlm.nih.gov/pubmed/33106549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75229-9
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