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Increased intestinal permeability and gut dysbiosis in the R6/2 mouse model of Huntington’s disease

Huntington’s disease (HD) is a progressive, multifaceted neurodegenerative disease associated with weight loss and gut problems. Under healthy conditions, tight junction (TJ) proteins maintain the intestinal barrier integrity preventing bacterial translocation from the intestinal lumen to the system...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Stan, Tiberiu Loredan, Soylu-Kucharz, Rana, Burleigh, Stephen, Prykhodko, Olena, Cao, Ling, Franke, Naomi, Sjögren, Marie, Haikal, Caroline, Hållenius, Frida, Björkqvist, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589489/
https://ncbi.nlm.nih.gov/pubmed/33106549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75229-9
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