Development of a Novel SPR Assay to Study CXCR4–Ligand Interactions

G protein-coupled receptors (GPCRs) are involved in a plethora of different diseases. Consequently, these proteins are considered as an important class of drug targets. Measuring detailed kinetic information on these types of proteins has been challenging. Surface plasmon resonance (SPR) can provide...

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Bibliographische Detailangaben
Veröffentlicht in:Biosensors (Basel)
Hauptverfasser: Boonen, Arnaud, Singh, Abhimanyu K., Hout, Anneleen Van, Das, Kalyan, Loy, Tom Van, Noppen, Sam, Schols, Dominique
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589327/
https://ncbi.nlm.nih.gov/pubmed/33096938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bios10100150
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