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Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction
Mechanical cues activate cardiac fibroblasts and induce differentiation into myofibroblasts, which are key steps for development of cardiac fibrosis. In vitro, the high stiffness of plastic culturing conditions will also induce these changes. It is therefore challenging to study resting cardiac fibr...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7588109/ https://ncbi.nlm.nih.gov/pubmed/33104742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241390 |
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