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Viral surface geometry shapes influenza and coronavirus spike evolution through antibody pressure

The evolution of circulating viruses is shaped by their need to evade antibody response, which mainly targets the glycoprotein (spike). However, not all antigenic sites are targeted equally by antibodies, leading to complex immunodominance patterns. We used 3D computational models to estimate antibo...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:bioRxiv
Egile nagusia: Amitai, Assaf
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587782/
https://ncbi.nlm.nih.gov/pubmed/33106808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.10.20.347641
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