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ASCL1 regulates neurodevelopmental transcription factors and cell cycle genes in brain tumors of glioma mouse models

Glioblastomas (GBMs) are incurable brain tumors with a high degree of cellular heterogeneity and genetic mutations. Transcription factors that normally regulate neural progenitors and glial development are aberrantly coexpressed in GBM, conferring cancer stem‐like properties to drive tumor progressi...

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Bibliografske podrobnosti
izdano v:Glia
Main Authors: Vue, Tou Yia, Kollipara, Rahul K., Borromeo, Mark D., Smith, Tyler, Mashimo, Tomoyuki, Burns, Dennis K., Bachoo, Robert M., Johnson, Jane E.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587013/
https://ncbi.nlm.nih.gov/pubmed/32573857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23873
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