ASCL1 regulates neurodevelopmental transcription factors and cell cycle genes in brain tumors of glioma mouse models

Glioblastomas (GBMs) are incurable brain tumors with a high degree of cellular heterogeneity and genetic mutations. Transcription factors that normally regulate neural progenitors and glial development are aberrantly coexpressed in GBM, conferring cancer stem‐like properties to drive tumor progressi...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Vue, Tou Yia, Kollipara, Rahul K., Borromeo, Mark D., Smith, Tyler, Mashimo, Tomoyuki, Burns, Dennis K., Bachoo, Robert M., Johnson, Jane E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587013/
https://ncbi.nlm.nih.gov/pubmed/32573857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23873
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