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Engineering the specificity of Streptococcus pyogenes sortase A by loop grafting
Sortases are a group of enzymes displayed on the cell‐wall of Gram‐positive bacteria. They are responsible for the attachment of virulence factors onto the peptidoglycan in a transpeptidation reaction through recognition of a pentapeptide substrate. Most housekeeping sortases recognize one specific...
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| Veröffentlicht in: | Proteins |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley & Sons, Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7586933/ https://ncbi.nlm.nih.gov/pubmed/32501594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25958 |
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