Reactive astrocytes express Aggregatin (FAM222A) in the brains of Alzheimer's disease and Nasu-Hakola disease

By combining genomic data and brain imaging data, a recent study has identified a novel gene named FAM222A that participates in the formation of amyloid-β (Aβ) plaques and brain atrophy in Alzheimer's disease (AD). FAM222A encodes a 47-kDa protein designated Aggregatin that accumulates in the c...

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Bibliographic Details
Published in:Intractable Rare Dis Res
Main Authors: Satoh, Jun-ichi, Kino, Yoshihiro, Yanaizu, Motoaki, Ishida, Tsuyoshi, Saito, Yuko
Format: Artigo
Language:Inglês
Published: International Research and Cooperation Association for Bio & Socio-Sciences Advancement 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586878/
https://ncbi.nlm.nih.gov/pubmed/33139980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5582/irdr.2020.03080
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