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Microglia express gamma-interferon-inducible lysosomal thiol reductase in the brains of Alzheimer's disease and Nasu-Hakola disease

Gamma-interferon-inducible lysosomal thiol reductase (GILT), expressed in antigen-presenting cells (APCs), facilitates the reduction of disulfide bonds of endocytosed proteins in the endocytic pathway and they are further processed for presentation of immunogenic peptides loaded on major histocompat...

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Detalhes bibliográficos
Publicado no:Intractable Rare Dis Res
Main Authors: Satoh, Jun-ichi, Kino, Yoshihiro, Yanaizu, Motoaki, Ishida, Tsuyoshi, Saito, Yuko
Formato: Artigo
Idioma:Inglês
Publicado em: International Research and Cooperation Association for Bio & Socio-Sciences Advancement 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290847/
https://ncbi.nlm.nih.gov/pubmed/30560017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5582/irdr.2018.01119
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