Microglia express ABI3 in the brains of Alzheimer's disease and Nasu-Hakola disease

Nasu-Hakola disease (NHD) is a rare autosomal recessive leukoencephalopathy caused by a loss-of-function mutation of either TYROBP (DAP12) or TREM2 expressed in microglia. A rare variant of the TREM2 gene encoding p.Arg47His causes a 3-fold increase in the risk for late-onset Alzheimer's diseas...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Intractable Rare Dis Res
Autores principales: Satoh, Jun-ichi, Kino, Yoshihiro, Yanaizu, Motoaki, Tosaki, Youhei, Sakai, Kenji, Ishida, Tsuyoshi, Saito, Yuko
Formato: Artigo
Lenguaje:Inglês
Publicado: International Research and Cooperation Association for Bio & Socio-Sciences Advancement 2017
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735279/
https://ncbi.nlm.nih.gov/pubmed/29259854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5582/irdr.2017.01073
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares