Microglia express ABI3 in the brains of Alzheimer's disease and Nasu-Hakola disease

Nasu-Hakola disease (NHD) is a rare autosomal recessive leukoencephalopathy caused by a loss-of-function mutation of either TYROBP (DAP12) or TREM2 expressed in microglia. A rare variant of the TREM2 gene encoding p.Arg47His causes a 3-fold increase in the risk for late-onset Alzheimer's diseas...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Intractable Rare Dis Res
Päätekijät: Satoh, Jun-ichi, Kino, Yoshihiro, Yanaizu, Motoaki, Tosaki, Youhei, Sakai, Kenji, Ishida, Tsuyoshi, Saito, Yuko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: International Research and Cooperation Association for Bio & Socio-Sciences Advancement 2017
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735279/
https://ncbi.nlm.nih.gov/pubmed/29259854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5582/irdr.2017.01073
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