RNA editing in cancer impacts mRNA abundance in immune response pathways

BACKGROUND: RNA editing generates modifications to the RNA sequences, thereby increasing protein diversity and shaping various layers of gene regulation. Recent studies have revealed global shifts in editing levels across many cancer types, as well as a few specific mechanisms implicating individual...

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Publicat a:Genome Biol
Autors principals: Chan, Tracey W., Fu, Ting, Bahn, Jae Hoon, Jun, Hyun-Ik, Lee, Jae-Hyung, Quinones-Valdez, Giovanni, Cheng, Chonghui, Xiao, Xinshu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586670/
https://ncbi.nlm.nih.gov/pubmed/33106178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02171-4
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