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Mysterious and fascinating: DNA polymerase ɩ remains enigmatic 20 years after its discovery

With the publication of the first paper describing the biochemical properties of DNA polymerase iota (polι), the question immediately arose as to why cells harbor such a low-fidelity enzyme which often violates the Watson-Crick base pairing rules? Yet 20 years after its discovery, the cellular funct...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Vaisman, Alexandra, Woodgate, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586464/
https://ncbi.nlm.nih.gov/pubmed/33087280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102914
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