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Mysterious and fascinating: DNA polymerase ɩ remains enigmatic 20 years after its discovery

With the publication of the first paper describing the biochemical properties of DNA polymerase iota (polι), the question immediately arose as to why cells harbor such a low-fidelity enzyme which often violates the Watson-Crick base pairing rules? Yet 20 years after its discovery, the cellular funct...

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Dettagli Bibliografici
Pubblicato in:DNA Repair (Amst)
Autori principali: Vaisman, Alexandra, Woodgate, Roger
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586464/
https://ncbi.nlm.nih.gov/pubmed/33087280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102914
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