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Extremely Amyloidogenic Single-Chain Analogues of Insulin’s H-Fragment: Structural Adaptability of an Amyloid Stretch

[Image: see text] Relatively short amino acid sequences often play a pivotal role in triggering protein aggregation leading to the formation of amyloid fibrils. In the case of insulin, various regions of A- and B-chains have been implicated as the most relevant to the protein’s amyloidogenicity. Her...

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Detaylı Bibliyografya
Yayımlandı:Langmuir
Asıl Yazarlar: Dec, Robert, Dzwolak, Wojciech
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2020
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586408/
https://ncbi.nlm.nih.gov/pubmed/32988199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.langmuir.0c01747
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