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The emergence of superstructural order in insulin amyloid fibrils upon multiple rounds of self-seeding

Typically, elongation of an amyloid fibril entails passing conformational details of the mother seed to daughter generations of fibrils with high fidelity. There are, however, several factors that can potentially prevent such transgenerational structural imprinting from perpetuating, for example het...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Surmacz-Chwedoruk, Weronika, Babenko, Viktoria, Dec, Robert, Szymczak, Piotr, Dzwolak, Wojciech
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997315/
https://ncbi.nlm.nih.gov/pubmed/27558445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32022
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