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The emergence of superstructural order in insulin amyloid fibrils upon multiple rounds of self-seeding

Typically, elongation of an amyloid fibril entails passing conformational details of the mother seed to daughter generations of fibrils with high fidelity. There are, however, several factors that can potentially prevent such transgenerational structural imprinting from perpetuating, for example het...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Surmacz-Chwedoruk, Weronika, Babenko, Viktoria, Dec, Robert, Szymczak, Piotr, Dzwolak, Wojciech
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997315/
https://ncbi.nlm.nih.gov/pubmed/27558445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32022
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