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Calcineurin/AKAP interactions: therapeutic targeting of a pleiotropic enzyme with a little help from its friends
The ubiquitous Ca(2+)/calmodulin-dependent phosphatase calcineurin is a key regulator of pathological cardiac hypertrophy whose therapeutic targeting in heart disease has been elusive due to its role in other essential biologic processes. Calcineurin is targeted to diverse intracellular compartments...
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| Udgivet i: | J Physiol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7586300/ https://ncbi.nlm.nih.gov/pubmed/30488951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276756 |
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