The mAKAPβ Scaffold Regulates Cardiac Myocyte Hypertrophy via Recruitment of Activated Calcineurin

mAKAPβ is the scaffold for a multimolecular signaling complex in cardiac myocytes that is required for the induction of neonatal myocyte hypertrophy. We now show that the pro-hypertrophic phosphatase calcineurin binds directly to a single site on mAKAPβ that does not conform to any of the previously...

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Autori principali: Li, Jinliang, Negro, Alejandra, Lopez, Johanna, Bauman, Andrea L., Henson, Edward, Dodge-Kafka, Kimberly, Kapiloff, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813376/
https://ncbi.nlm.nih.gov/pubmed/19883655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.10.023
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