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Bidirectional regulation of HDAC5 by mAKAPβ signalosomes in cardiac myocytes

Class IIa histone deacetylases (HDACs) are transcriptional repressors whose nuclear export in the cardiac myocyte is associated with the induction of pathological gene expression and cardiac remodeling. Class IIa HDACs are regulated by multiple, functionally opposing post-translational modifications...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Dodge-Kafka, Kimberly L., Gildart, Moriah, Li, Jinliang, Thakur, Hrishikesh, Kapiloff, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940533/
https://ncbi.nlm.nih.gov/pubmed/29522762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.03.001
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