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Arctiin Antagonizes Triptolide-Induced Hepatotoxicity via Activation of Nrf2 Pathway

Triptolide (TP) is the most effective ingredient found in the traditional Chinese herbal Tripterygium wilfordii Hook F, and it is widely used in therapies of autoimmune and inflammatory disorders. However, the hepatotoxicity induced by TP has restricted its use in clinical trials. Arctiin is known a...

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Res Int
Hauptverfasser: Zhou, Yuyan, Xia, Li, Yao, Weiqiang, Han, Jun, Wang, Guodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586171/
https://ncbi.nlm.nih.gov/pubmed/33123566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2508952
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