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p21 can be a barrier to ferroptosis independent of p53

Traditionally, the p21 protein has been viewed as limiting cancer progression and promoting aging. In contrast, there are reports that p21 can enhance cancer survival and limit tissue damage, depending on the tissue of origin and type of stressor involved. Here, we provide evidence to support these...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Venkatesh, Divya, Stockwell, Brent R., Prives, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585094/
https://ncbi.nlm.nih.gov/pubmed/32979260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103961
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