Hypoxia Impairs NK Cell Cytotoxicity through SHP-1-Mediated Attenuation of STAT3 and ERK Signaling Pathways

Natural killer (NK) cells are innate immune effectors with potent antitumor activity. However, tumor cells can create an immunosuppressive microenvironment to escape immune surveillance. Although accumulating evidence indicates that microenvironmental hypoxia plays an important role in favoring tumo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol Res
Prif Awduron: Teng, Rui, Wang, Yanmeng, Lv, Nan, Zhang, Dan, Williamson, Ramone A., Lei, Lei, Chen, Ping, Lei, Li, Wang, Baiyan, Fu, Jiaqi, Liu, Xuna, He, Aili, O'Dwyer, Michael, Hu, Jinsong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584946/
https://ncbi.nlm.nih.gov/pubmed/33123602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4598476
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg