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Immunomodulation by anticancer cell cycle inhibitors

Cell cycle proteins that are often dysregulated in malignant cells, such as cyclin-dependent kinase 4 (CDK4) and CDK6, have attracted considerable interest as potential targets for cancer therapy. In this context, multiple inhibitors of CDK4 and CDK6 have been developed, including three small molecu...

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Pubblicato in:Nat Rev Immunol
Autori principali: Petroni, Giulia, Formenti, Silvia C., Chen-Kiang, Selina, Galluzzi, Lorenzo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584736/
https://ncbi.nlm.nih.gov/pubmed/32346095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-020-0300-y
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