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Diastereodivergent chiral aldehyde catalysis for asymmetric 1,6-conjugated addition and Mannich reactions

Chiral aldehyde catalysis is a burgeoning strategy for the catalytic asymmetric α-functionalization of aminomethyl compounds. However, the reaction types are limited and to date include no examples of stereodivergent catalysis. In this work, we disclose two chiral aldehyde-catalysed diastereodiverge...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Wen, Wei, Luo, Ming-Jing, Yuan, Yi, Liu, Jian-Hua, Wu, Zhu-Lian, Cai, Tian, Wu, Zhao-Wei, Ouyang, Qin, Guo, Qi-Xiang
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584650/
https://ncbi.nlm.nih.gov/pubmed/33097724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19245-3
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