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Chiral ammonium betaine-catalyzed asymmetric Mannich-type reaction of oxindoles

A highly diastereo- and enantioselective Mannich-type reaction of 3-aryloxindoles with N-Boc aldimines was achieved under the catalysis of axially chiral ammonium betaines. This catalytic method provides a new tool for the construction of consecutive quaternary and tertiary stereogenic carbon center...

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Detalles Bibliográficos
Publicado en:Beilstein J Org Chem
Main Authors: Torii, Masahiro, Kato, Kohsuke, Uraguchi, Daisuke, Ooi, Takashi
Formato: Artigo
Idioma:Inglês
Publicado: Beilstein-Institut 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082719/
https://ncbi.nlm.nih.gov/pubmed/27829916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.199
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