Fabrication of tri-layered electrospun polycaprolactone mats with improved sustained drug release profile

Modulation of initial burst and long term release from electrospun fibrous mats can be achieved by sandwiching the drug loaded mats between hydrophobic layers of fibrous polycaprolactone (PCL). Ibuprofen (IBU) loaded PCL fibrous mats (12% PCL-IBU) were sandwiched between fibrous polycaprolactone lay...

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Pubblicato in:Sci Rep
Autori principali: Kamath, S. Manjunath, Sridhar, K., Jaison, D., Gopinath, V., Ibrahim, B. K. Mohamed, Gupta, Nilkantha, Sundaram, A., Sivaperumal, P., Padmapriya, S., Patil, S. Shantanu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584580/
https://ncbi.nlm.nih.gov/pubmed/33097770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74885-1
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