Fabrication of tri-layered electrospun polycaprolactone mats with improved sustained drug release profile

Modulation of initial burst and long term release from electrospun fibrous mats can be achieved by sandwiching the drug loaded mats between hydrophobic layers of fibrous polycaprolactone (PCL). Ibuprofen (IBU) loaded PCL fibrous mats (12% PCL-IBU) were sandwiched between fibrous polycaprolactone lay...

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Publicado en:Sci Rep
Autores principales: Kamath, S. Manjunath, Sridhar, K., Jaison, D., Gopinath, V., Ibrahim, B. K. Mohamed, Gupta, Nilkantha, Sundaram, A., Sivaperumal, P., Padmapriya, S., Patil, S. Shantanu
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584580/
https://ncbi.nlm.nih.gov/pubmed/33097770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74885-1
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