Fabrication of tri-layered electrospun polycaprolactone mats with improved sustained drug release profile

Modulation of initial burst and long term release from electrospun fibrous mats can be achieved by sandwiching the drug loaded mats between hydrophobic layers of fibrous polycaprolactone (PCL). Ibuprofen (IBU) loaded PCL fibrous mats (12% PCL-IBU) were sandwiched between fibrous polycaprolactone lay...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kamath, S. Manjunath, Sridhar, K., Jaison, D., Gopinath, V., Ibrahim, B. K. Mohamed, Gupta, Nilkantha, Sundaram, A., Sivaperumal, P., Padmapriya, S., Patil, S. Shantanu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584580/
https://ncbi.nlm.nih.gov/pubmed/33097770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74885-1
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