Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function: a randomised controlled trial

BACKGROUND: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical performance. METHODS: We conducted a randomised, doubl...

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Vydáno v:Age Ageing
Hlavní autoři: Witham, Miles D, Clarke, Clare L, Hutcheon, Anita, Gingles, Christopher, Gandy, Stephen, Priba, Lukasz, Nicholas, Richard S, Cavin, Ian, Sumukadas, Deepa, Struthers, Allan D, George, Jacob
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583523/
https://ncbi.nlm.nih.gov/pubmed/32318695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ageing/afaa061
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