Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function: a randomised controlled trial

BACKGROUND: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical performance. METHODS: We conducted a randomised, doubl...

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Detalhes bibliográficos
Publicado no:Age Ageing
Main Authors: Witham, Miles D, Clarke, Clare L, Hutcheon, Anita, Gingles, Christopher, Gandy, Stephen, Priba, Lukasz, Nicholas, Richard S, Cavin, Ian, Sumukadas, Deepa, Struthers, Allan D, George, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583523/
https://ncbi.nlm.nih.gov/pubmed/32318695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ageing/afaa061
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