Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function: a randomised controlled trial

BACKGROUND: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical performance. METHODS: We conducted a randomised, doubl...

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Publicat a:Age Ageing
Autors principals: Witham, Miles D, Clarke, Clare L, Hutcheon, Anita, Gingles, Christopher, Gandy, Stephen, Priba, Lukasz, Nicholas, Richard S, Cavin, Ian, Sumukadas, Deepa, Struthers, Allan D, George, Jacob
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583523/
https://ncbi.nlm.nih.gov/pubmed/32318695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ageing/afaa061
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