Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function: a randomised controlled trial

BACKGROUND: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical performance. METHODS: We conducted a randomised, doubl...

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Dettagli Bibliografici
Pubblicato in:Age Ageing
Autori principali: Witham, Miles D, Clarke, Clare L, Hutcheon, Anita, Gingles, Christopher, Gandy, Stephen, Priba, Lukasz, Nicholas, Richard S, Cavin, Ian, Sumukadas, Deepa, Struthers, Allan D, George, Jacob
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583523/
https://ncbi.nlm.nih.gov/pubmed/32318695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ageing/afaa061
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