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T follicular regulatory cells: Guardians of the germinal centre?

It is a central tenet of the clonal selection theory, that lymphocyte repertoires are tolerized to self‐antigens during their ontogeny. Germinal centres are the sites in secondary lymphoid tissues where B cells undergo affinity maturation and class‐switching to produce high‐affinity antibodies. This...

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Detalhes bibliográficos
Publicado no:Scand J Immunol
Main Authors: Fahlquist Hagert, Cecilia, Degn, Søren E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583367/
https://ncbi.nlm.nih.gov/pubmed/32697349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/sji.12942
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