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Regulatory T cells and control of the germinal centre response

Germinal centres (GCs) are specialised lymphoid microenvironments that form in secondary B-cell follicles upon exposure to T-dependent antigens. In the GC, clonal expansion, selection and differentiation of GC B cells result in the production of high-affinity plasma cells and memory B cells that pro...

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Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: Vanderleyden, Ine, Linterman, Michelle A, Smith, Kenneth GC
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289055/
https://ncbi.nlm.nih.gov/pubmed/25606598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0471-7
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