AR12286 Alleviates TGF-β-Related Myofibroblast Transdifferentiation and Reduces Fibrosis after Glaucoma Filtration Surgery

Scar formation can cause the failure of glaucoma filtration surgery. We investigated the effect of AR12286, a selective Rho-associated kinase inhibitor, on myofibroblast transdifferentiation and intraocular pressure assessment in rabbit glaucoma filtration surgery models. Cell migration and collagen...

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Publicado no:Molecules
Main Authors: Cheng, Wen-Sheng, Chen, Ching-Long, Chen, Jiann-Torng, Lin, Le-Tien, Pao, Shu-I, Chen, Yi-Hao, Lu, Da-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583051/
https://ncbi.nlm.nih.gov/pubmed/32993110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194422
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