Lefty-1 alleviates TGF-β1-induced fibroblast–myofibroblast transdifferentiation in NRK-49F cells

Fibroblast activation and proliferation are important for fibroblast–myofibroblast transdifferentiation, a crucial process in the pathological changes that define renal interstitial fibrosis. The left–right determination factor (Lefty) is an important cytokine of the transforming growth factor (TGF)...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Des Devel Ther
Main Authors: Zhang, Lijun, Zhang, Jie, Xu, Changgeng, Zhou, Xiangjun, Wang, Wei, Zheng, Renping, Hu, Wei, Wu, Pin
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2015
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544629/
https://ncbi.nlm.nih.gov/pubmed/26316705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86770
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