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Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity

Brown adipose tissue (BAT) is an important target for obesity treatment and prevention. Soluble epoxide hydrolase (sEH) converts bioactive epoxy fatty acids (EpFAs) into less active diols. sEH inhibitors (sEHI) are beneficial in many chronic diseases by stabilizing EpFAs. However, roles of sEH and s...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Overby, Haley, Yang, Yang, Xu, Xinyun, Graham, Katherine, Hildreth, Kelsey, Choi, Sue, Wan, Debin, Morisseau, Christophe, Zeldin, Darryl C., Hammock, Bruce D., Wang, Shu, Bettaieb, Ahmed, Zhao, Ling
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582898/
https://ncbi.nlm.nih.gov/pubmed/32987880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197039
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