Pharmacological Inhibition of Soluble Epoxide Hydrolase by t-TUCB Improves Brown Adipose Tissue Activities in Diet-Induced Obesity

OBJECTIVES: Brown adipose tissue (BAT), responsible for energy expenditure through nonshivering thermogenesis, has emerged as a novel target for obesity treatment and prevention. Soluble epoxide hydrolase (sEH), encoded by Ephx2 gene, is a cytosolic enzyme that converts epoxy fatty acids (EpFAs) tha...

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Detalles Bibliográficos
Publicado en:Curr Dev Nutr
Main Authors: Yang, Yang, Xu, Xinyun, Graham, Katie, Bettaieb, Ahmed, Morisseau, Christophe, Hammock, Bruce, Wang, Shu, Zhao, Ling
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Obesity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257431/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa063_101
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