Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity

Brown adipose tissue (BAT) is an important target for obesity treatment and prevention. Soluble epoxide hydrolase (sEH) converts bioactive epoxy fatty acids (EpFAs) into less active diols. sEH inhibitors (sEHI) are beneficial in many chronic diseases by stabilizing EpFAs. However, roles of sEH and s...

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Pubblicato in:Int J Mol Sci
Autori principali: Overby, Haley, Yang, Yang, Xu, Xinyun, Graham, Katherine, Hildreth, Kelsey, Choi, Sue, Wan, Debin, Morisseau, Christophe, Zeldin, Darryl C., Hammock, Bruce D., Wang, Shu, Bettaieb, Ahmed, Zhao, Ling
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582898/
https://ncbi.nlm.nih.gov/pubmed/32987880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197039
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