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Cytotoxic and Senolytic Effects of Methadone in Combination with Temozolomide in Glioblastoma Cells

Methadone is an analgesic drug used for pain treatment and heroin substitution. Recently, methadone has been proposed to be useful also for cancer therapy, including glioblastoma multiforme (GBM), the most severe form of brain cancer, because experiments on cultured glioma cells treated with doxorub...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kaina, Bernd, Beltzig, Lea, Piee-Staffa, Andrea, Haas, Bodo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582495/
https://ncbi.nlm.nih.gov/pubmed/32977591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197006
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