Targeting c-IAP1, c-IAP2, and Bcl-2 Eliminates Senescent Glioblastoma Cells Following Temozolomide Treatment

SIMPLE SUMMARY: Despite extensive research, malignant glioma remains the most aggressive and fatal type of brain tumor. Following resection, therapy is based on radiation concomitant with the methylating agent temozolomide (TMZ), followed by adjuvant high-dose TMZ. In previous work, we showed that f...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Schwarzenbach, Christian, Tatsch, Larissa, Brandstetter Vilar, Juliana, Rasenberger, Birgit, Beltzig, Lea, Kaina, Bernd, Tomicic, Maja T., Christmann, Markus
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306656/
https://ncbi.nlm.nih.gov/pubmed/34298797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143585
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