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Ring-Closing Metathesis Approaches towards the Total Synthesis of Rhizoxins
Efforts are described towards the total synthesis of the bacterial macrolide rhizoxin F, which is a potent tubulin assembly and cancer cell growth inhibitor. A significant amount of work was expanded on the construction of the rhizoxin core macrocycle by ring-closing olefin metathesis (RCM) between...
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| Publié dans: | Molecules |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7582377/ https://ncbi.nlm.nih.gov/pubmed/33023218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194527 |
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