Pharmacokinetics and other risk factors for kanamycin-induced hearing loss in patients with multi-drug resistant tuberculosis

OBJECTIVE: The toxicity associated with the use of kanamycin includes irreversible hearing loss. There is limited data describing the relationship between hearing loss and kanamycin pharmacokinetics (PK). We explored the association of kanamycin PK with hearing loss in patients on MDR-TB treatment....

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Udgivet i:Int J Audiol
Main Authors: Ghafari, Nazanin, Court, Richard, Chirehwa, Maxwell Tawanda, Wiesner, Lubbe, Petersen, Lucretia, Maartens, Gary, Gumbo, Tawanda, McIlleron, Helen, Ramma, Lebogang
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582222/
https://ncbi.nlm.nih.gov/pubmed/31739701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14992027.2019.1690170
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