Pharmacokinetics and other risk factors for kanamycin-induced hearing loss in patients with multi-drug resistant tuberculosis

OBJECTIVE: The toxicity associated with the use of kanamycin includes irreversible hearing loss. There is limited data describing the relationship between hearing loss and kanamycin pharmacokinetics (PK). We explored the association of kanamycin PK with hearing loss in patients on MDR-TB treatment....

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Detalhes bibliográficos
Publicado no:Int J Audiol
Main Authors: Ghafari, Nazanin, Court, Richard, Chirehwa, Maxwell Tawanda, Wiesner, Lubbe, Petersen, Lucretia, Maartens, Gary, Gumbo, Tawanda, McIlleron, Helen, Ramma, Lebogang
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582222/
https://ncbi.nlm.nih.gov/pubmed/31739701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14992027.2019.1690170
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