Tumor Phylogeny Topology Inference via Deep Learning

Principled computational approaches for tumor phylogeny reconstruction via single-cell sequencing typically aim to build the most likely perfect phylogeny tree from the noisy genotype matrix – which represents genotype calls of single cells. This problem is NP-hard, and as a result, existing approac...

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Bibliographic Details
Published in:iScience
Main Authors: Sadeqi Azer, Erfan, Haghir Ebrahimabadi, Mohammad, Malikić, Salem, Khardon, Roni, Sahinalp, S. Cenk
Format: Artigo
Language:Inglês
Published: Elsevier 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582044/
https://ncbi.nlm.nih.gov/pubmed/33117968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101655
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