Efficacy of afatinib for pulmonary adenocarcinoma with leptomeningeal metastases harboring an epidermal growth factor receptor complex mutation (exon 19del+K754E): A case report

RATIONALE: Liquid biopsy of cerebrospinal fluid (CSF) and sequencing of cell-free DNA has rarely been used to identify epidermal growth factor receptor (EGFR) mutations, which can guide the design of precise, personalized treatment for patients with leptomeningeal metastasis from lung adenocarcinoma...

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Bibliographic Details
Published in:Medicine (Baltimore)
Main Authors: Ma, Chunhua, Liu, Mei, Mu, Ning, Li, Jinduo, Li, Lin, Jiang, Rong
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2020
Subjects:
5700
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581162/
https://ncbi.nlm.nih.gov/pubmed/33120820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000022851
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