Effective Treatment With Afatinib of Lung Adenocarcinoma With Leptomeningeal Metastasis Harboring the Exon 18 p.G719A Mutation in the EGFR Gene Was Detected in Cerebrospinal Fluid: A Case Report

Background: In patients with lung adenocarcinoma and leptomeningeal metastases, it remains unknown whether non-classical mutations in the epidermal growth factor receptor (EGFR) gene can be detected in the cerebrospinal fluid (CSF) and how it may be used to design directed therapy. Methods: On April...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Ma, Chunhua, Wang, Shuyuan, Mu, Ning, Li, Jinduo, Liu, Mei, Li, Lin, Jiang, Rong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7506151/
https://ncbi.nlm.nih.gov/pubmed/33014823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01635
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